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Contrast Nephropathy recommendations
New Antiplatelet Agents
New Strategies and Devices to Manage Cardiogenic Shock
The Predictive Value of Computed Tomography Calcium Scores: A Comparison with Quantitative Volumetric Intravascular Ultrasound
Will Cangrelor Replace Clopidogrel and IIb IIIa Inhibitors in the Lab



Height Influences Risk of CAD (C Nelson, et al. NEJM 2015 Online)

The mechanism underpinning the relationship between height and the risk of CAD is unknown. A genetic-based study has identified an association between shorter height and increased risk of CAD. This association is linked to adverse lipid profile and overlapping genetic pathways involved in development and atherosclerosis.

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Lipid Lowering Benefits Both Sexes

The efficacy of statins in men versus women is unclear. A meta-analysis of 27 studies comparing statin efficacy upon major vascular events, major coronary events, stroke, coronary revascularization, and mortality has indicated that both men and women derive similar benefits with statin therapy.

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Weight and the Risk of Dementia

The association between body weight and risk of dementia remains a subject of debate. A retrospective study of 1,958,191 individuals derived from the UK Clinical Practice Research Datalink has indicated that as compared with a healthy weight, underweight individuals had a 34% higher risk of dementia. In addition, very obese people had a 29% lower risk of dementia.

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Total Abandonment of Thrombectomy in STEMI

Manual thrombectomy in patients presenting with STEMI has been proposed to reduce distal embolization and improve clinical outcomes. The TOTAL study of 10,732 STEMI patients has indicated that such an approach does not reduce the risk of CV death, recurrent MI, cardiogenic shock, or heart failure within 180 days. Thrombectomy was also associated with an increased rate of stroke within 30 days.

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Strokes in TAVR Is it a Deal Breaker?
- Samir Kapadia, MD
CoreValve US Pivotal Trial
- John V. Conte, MD
Myocardial infarction with no obstructive coronary atherosclerosis
- Giampaolo Niccoli, MD, PhD
Incidence, Predictors, and Prognostic Impact of Late Bleeding (≥30 days) Complications after Transcatheter Aortic Valve Replacement (TAVR)
- Philippe Généreux, MD
Minimizing Femoral Artery Access Complications during PCI
- Michael S. Lee, MD

Live Case Demonstration from Kusatsu Heart Center
Osamu Hatoh, MD
Treating CTO via Radial?
Richard R. Heuser, MD
Patient Selection for CTO Recanalization: What Are the Appropriate Criteria?
Tarek Helmy, MD
Treating CTOs: Is There Enough Evidence-Based Data or do We Need Further Randomized Clinical Trials?
Gerald S. Werner, MD, PhD
Indication for CTO PCI: Clinical Rationale and Appropriateness
J. Aaron Grantham, MD
 Click here to visit the WEBEX archives

Genetically Determined Height and Coronary Artery Disease.
C Nelson, et al.
NEJM 2015 Online
Randomized Trial of Primary PCI With or Without Routine Manual Thrombectomy.
S Jolly, et al.
NEJM 2015; 372:1389-1398
Surgical Ablation of Atrial Fibrillation during Mitral-Valve Surgery.
A Gillinov, et al.
NEJM 2015; 372:1399-1409
Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery.
M Steiner, et al.
NEJM 2015; 372:1419-1429
Oral Anticoagulation, Aspirin, or No Therapy in Patients With Nonvalvular AF With 0 or 1 Stroke Risk Factor Based on the CHA2DS2-VASc Score.
G Lip, et al.
JACC 2015; 65:1385-1394
Readmissions After Carotid Artery Revascularization in the Medicare Population.
M Al-Damluji, et al.
JACC 2015; 65:1398-1408
Association of Spontaneous Bleeding and Myocardial Infarction With Long-Term Mortality After Percutaneous Coronary Intervention.
D Kazi, et al.
JACC 2015; 65:1411-1420
Exposure to Parental Smoking in Childhood Is Associated With Increased Risk of Carotid Atherosclerotic Plaque in Adulthood: The Cardiovascular Risk in Young Finns Study.
H West, et al.
Circ 2015; 131:1239-1246
Optimal Medical Therapy Improves Clinical Outcomes in Patients Undergoing Revascularization With Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: Insights From the Synergy Between Percutaneous Coronary Intervention With TAXUS and Cardiac Surgery (SYNTAX) Trial at the 5-Year Follow-Up.
J Iqbal, et al.
Circ 2015; 131:1269-1277
Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China: The CSPPT Randomized Clinical Trial.
Y Huo, et al.
JAMA 2015; 313:1325-1335
BMI and Risk of Dementia in Two Million People Over Two Decades: A Retrospective Cohort Study.
N Qizilbash, et al.
The Lancet Diabetes & Endocrinology 2015 Online
Efficacy and Safety of LDL-Lowering Therapy Among Men and Women: Meta-Analysis of Individual Data From 174?000 Participants in 27 Randomised Trials.
CTT Collaboration.
The Lancet 2015; 385:1397-1405

Poll Archives
CoreValve US Pivotal Trial - Transcatheter Aortic Valve Replacement or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting
John V. Conte, M.D.
Alexandra Lansky, M.D.
The REGULATE-PCI Randomized Clinical Trial
Roxana Mehran, M.D.
Marc S. Sabatine, M.D., M.P.H.
Promise Trial
Pamela S. Douglas, M.D.
CoreValve US Pivotal Trial - 2-Year Outcomes
Michael J Reardon, M.D., F.A.C.C.
Sanjit Jolly, M.D.
Rajeev K. Pathak, M.D.
(PROMISE) Trial: Economic Outcomes
Daniel B. Mark, M.D., M.P.H.
Drug-Resistant Hypertension in an Asian Population
Byeong-Keuk Kim, M.D.
Reduced Blood Pressure Lowering Effect of Catheter-Based Renal Denervation in Patients with Isolated Systolic Hypertension: Data from Pooled SYMPLICITY HTN Trials
Felix Mahfoud, M.D.
BEST Trial
Seung-Jung Park, M.D., PhD
Outcomes of the Initial Experience with Commercial Transcatheter Mitral Valve Repair in the U.S.
Paul Sorajja, M.D.
Clinical and Echocardiographic Outcomes at 30 Days with the SAPIEN 3 TAVR System in Inoperable, High-Risk and Intermediate-Risk AS Patients
Susheel Kodali, M.D.
M. Valgimigli, M.D., PhD
C. Michael Gibson, M.S., M.D.
Five-Year Outcomes after Randomization to Transcatheter or Surgical Aortic Valve Replacement: Final Results of The PARTNER 1 Trial
Michael J. Mack, M.D.
Relation Between Frailty and Outcomes After Transcatheter Aortic Valve Replacement
Philip Green, M.D.
Effect of the PCSK9 Inhibitor Evolocumab on Cardiovascular Outcomes
Marc S. Sabatine, M.D., M.P.H.

Complex Patients Today and Tomorrow: Medtronic DES solutions from Resolute Integrity to bioresorbable stents
Prof. Sigmund Silber, MD
First Report on the Pivotal DESolve Nx trial: 6-month Clinical and Multimodality Imaging Results
Alexandre Abizaid, MD, PhD
One-Year Outcomes in 1010 Unselected Patients Treated with the PROMUS Element Everolimus-Eluting Stent: The Multicenter PROMUS Element European Post-Approval Surveillance Study
Raul Moreno, MD, et al.
Two-year clinical outcomes in the EVOLVE FHU trial
Ian Meredith, MD, PhD
Stephan Windecker, MD, et al.

Outcomes in More Than 7000 Patients With Diabetes After Implantation of the Resolute Zotarolimus-eluting Stent
Rosli Mohd Ali, MD
Safety update and long-term clinical outcomes from all studies in the RESOLUTE Global Clinical Program
Carlo Di Mario, MD
Final Five-year Outcomes from the Randomized Comparison of Zotarolimus-eluting Stents With Everolimus-eluting Stents in the RESOLUTE All Comers Trial
Stephan Windecker, MD
Angina Status & TLF Creep: Bioabsorbable Stents (BAS) & Drug-Eluting Stents (DES)
Medtronic, Inc.
Clinical outcomes associated with dual antiplatelet therapy interruption following implantation of the ResoluteTM zotarolimus-eluting stent
Stephan Windecker, MD
Four-year Outcomes from the Randomized Comparison of a Zotarolimus-eluting and an Everolimus-eluting Stent in the RESOLUTE All Comers Trial
Patrick W Serruys MD, PhD
Resolute in Bifurcation Lesions: Data from the RESOLUTE Clinical Program
Prof. Ran Kornowski, MD

First US commercial procedures with the Watchman device

Medtronic announces SPYRAL HTN global clinical trial programme for renal denervation

CoreValve receives first TAVR valve-in-valve indication

First Commercial Procedures in the United States Performed With Boston Scientific’s Watchman Device

The Medicines Company’s Cangrelor Approved in Europe

New Indication Allows Brilinta to Be Crushed for Patients With Difficulty Swallowing

Medtronic’s CoreValve TAVR System Approved in Japan

FDA Approves Valve-in-Valve Procedures With CoreValve TAVR System

Medtronic CoreValve® System Receives FDA Approval for Transcatheter Valve-In-Valve Procedures


Infraredx Launches Advanced TVC Imaging System and TVC Muller Extended Bandwidth NIRS-IVUS Catheter

Medtronic Initiates Pivotal Studies of Resolute Onyx(TM) Drug-Eluting Stent in United States

Toshiba’s Infinix 4DCT Receives FDA Clearance with Aquilion PRIME CT Configuration

Boston Scientific Announces Definitive Agreement To Acquire American Medical Systems' Urology Portfolio For Up To $1.65 Billion

Penumbra Launches POD Embolization Anchoring Device at SIR

Boston Scientific to Acquire American Medical Systems’ Urology Portfolio

ArtVentive Introduces EOS Device in the United States

Vascutek to Distribute Vascular Flow Technologies’ Spiral Flow Grafts in Europe

Cardinal Health to Acquire Cordis

Teleflex Awarded Dialysis Agreement With Premier

Merit Medical’s One Snare System Cleared by FDA
Angiomyogenesis & Cell Therapy
Carotid Interventions

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